Figure 5.

Recommended insulin delivery rates for the P, UW, and Y algorithms assuming a subject initiates therapy at 180 mg/dl and does not respond to insulin (analogous to a hyperglycemic clamp). Portland protocol is shifted back in time by 2 min and the Y protocol forward by 2 min to prevent overlap of symbols. All algorithms effect a continuous rise in delivery. The Y and P algorithms initiate therapy with a concomitant bolus. The P protocol continues with adjunctive boluses on each incremental step.