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. Author manuscript; available in PMC: 2009 Oct 27.
Published in final edited form as: J Lipid Res. 2005 Jul 1;46(9):1933–1943. doi: 10.1194/jlr.M500101-JLR200

Fig. 3.

Fig. 3

The induction of apoptosis by OxLDL and 7KC is suppressed in ACAT-1-deficient (ACAT-1-/-) peritoneal macrophages. Resident peritoneal macrophages from wild-type and ACAT-1-/- mice were isolated and treated for 24 h with OxLDL (50 μg/ml), 7KC (10 μg/ml), or vehicle, as indicated. MPMs were then subjected to in situ TUNEL analysis as described for Fig. 2. The results shown are representative of three independent experiments. * P < 0.001 and ** P < 0.0005 versus OxLDL- and 7KC-treated controls, respectively. Error bars represent standard deviation.