Table 2. Summary characteristics for the 7109 eligible BRCA1 and BRCA2 carriers used in the analysis and typed for either single nucleotide polymorphism (SNP).
| BRCA1 | BRCA2 | |||
|---|---|---|---|---|
| Characteristic | Unaffected | Breast cancer | Unaffected | Breast cancer |
| Number | 2055 | 2567 | 1051 | 1436 |
| Person-years follow-up | 87 571 | 104 679 | 46 315 | 63 080 |
| Median age at censure (IQR) | 41 (33–51) | 40 (34–46) | 42 (34–52) | 43 (37–50) |
| Age at censure (years), N (%) | ||||
| <30 | 327 (15.9) | 225 (8.8) | 139 (13.2) | 78 (5.4) |
| 30–39 | 584 (28.4) | 1052 (41.0) | 296 (28.1) | 462 (32.2) |
| 40–49 | 574 (27.9) | 880 (34.3) | 286 (27.2) | 511 (35.6) |
| 50–59 | 364 (17.7) | 296 (11.5) | 196 (18.7) | 278 (19.4) |
| 60–69 | 134 (6.5) | 87 (3.4) | 82 (7.8) | 81 (5.6) |
| 70+ | 72 (3.5) | 27 (1.0) | 52 (4.9) | 26 (1.8) |
| Year of birth, N (%) | ||||
| <1920 | 18 (0.9) | 32 (1.3) | 12 (1.1) | 10 (0.7) |
| 1920–29 | 63 (3.1) | 117 (4.6) | 39 (3.7) | 83 (5.8) |
| 1930–39 | 171 (8.3) | 267 (10.4) | 96 (9.1) | 196 (13.7) |
| 1940–49 | 326 (15.9) | 657 (25.6) | 143 (13.6) | 358 (24.9) |
| 1950–59 | 481 (23.4) | 820 (31.9) | 241 (22.9) | 459 (32.0) |
| 1960+ | 996 (48.5) | 674 (26.3) | 520 (49.5) | 330 (23.0) |
Abbreviation: IQR=interquartile range.