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. 2009 Oct 13;101(8):1469–1480. doi: 10.1038/sj.bjc.6605275

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Copyright © 2009 Cancer Research UK

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(A) Unsupervised hierarchical clustering of the nine ESR1-negative BRCA1 tumours using the gene-set #2. Two subgroup/class/clusters, a (left branch) and b (right branch), are observed, showing differences in the magnitude of expression of genes related to the immune response. (B) Unsupervised hierarchical clustering of the nine ESR1-negative BRCA1 tumours using transcription factor genes of the REL/NFκB family. The same subgroup/class/clusters (a and b) as those found using gene-set #2 are observed.