Table 2.

Final Model of the Hazard Ratio^a of Renal Cell Cancer in Relation to Flavonoid and Fish Intake Stratified by Body Mass Index, Alpha-Tocopherol Beta-Carotene Cancer Prevention Study, 1985–2002

	Body Mass Index						Pinteractionb
	All Levels		Above (>26 kg/m2) the Median		Below (<26 kg/m2) the Median
	Hazard Ratio	95% Confidence Interval	Hazard Ratio	95% Confidence Interval	Hazard Ratio	95% Confidence Interval
Quercetin, mg/day
≤4.8	Reference group		Reference group		Reference group
>4.8–6.6	0.8	0.6, 1.1	0.8	0.5, 1.3	0.8	0.5, 1.3
>6.6–9.1	0.6	0.4, 0.9	0.7	0.4, 1.1	0.6	0.3, 1.0
>9.1	0.6	0.4, 0.9	0.6	0.4, 1.0	0.7	0.4, 1.2
Ptrend	0.015		0.045		0.142		0.613
Baltic herring, g/day
≤2.1	Reference group		Reference group		Reference group
>2.1–6.5	1.5	1.0, 2.2	1.4	0.8, 2.4	1.5	0.8, 2.8
>6.5–12.2	1.8	1.2, 2.6	1.7	1.0, 2.8	2.0	1.1, 3.6
>12.2	2.0	1.4, 3.0	1.6	1.0, 2.7	2.7	1.5, 4.9
Ptrend	<0.001		0.090		<0.001		0.110

^aAll hazard ratios were adjusted for age, body mass index, pack-years of smoking, systolic blood pressure, alcohol intake, leisure time physical activity, urban residence, educational level, and dietary intakes of quercetin and Baltic herring. All dietary intake variables were energy adjusted.

^bP_interaction values are included for the multiplicative interaction between the continuous variables body mass index and each respective dietary intake variable.