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. Author manuscript; available in PMC: 2010 May 8.
Published in final edited form as: Cell Host Microbe. 2009 May 8;5(5):476–486. doi: 10.1016/j.chom.2009.03.011

Figure 2.

Figure 2

The iroBC locus confers lipocalin-2 resistance by overcoming iron limitation. (A) Growth of the S. Typhimurium wild type or an isogenic iroBC mutant in medium from collected from polarized T84 cells that had either not been stimulated with cytokines (control, open bars) or had been stimulated with IL–17 and IL–22 for 24 hours (IL–17 + IL–22, closed bars). Bacterial numbers were determined 5 hours after inoculation with 103 bacteria. (B) Bacterial growth in rich medium (LB broth). (C) Bacterial growth in tissue culture medium (DMEM) supplemented with lipocalin-2 (LCN), ferrioxamine B (FoxB) or containing no supplements. ND, not determined. All data represent means ± standard deviation from at least three different experiments.