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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Exp Eye Res. 2009 Feb 28;89(2):124–125. doi: 10.1016/j.exer.2009.02.011

Fig.

Fig

Model of structure of IL-1α and expression in unwounded and wounded rabbit corneas. A. Model structure of human interleukin-1 alpha. B. IL-1α is expressed constitutively throughout the corneal epithelium (arrowheads, red), but appears to be most highly expressed in apical epithelial cells. Note that little IL-1α is associated with keratocyte cells in the stroma of the unwounded cornea. Mag. 500X C. At one month after injury (in this case -9 diopter PRK that triggers haze and myofibroblast development) IL-1α is now detected in stromal cells (arrows, red), in addition to continued expression in the healed epithelium (arrowheads, red). Blue stain is DAPI staining of cell nuclei. Mag. 500X.