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. Author manuscript; available in PMC: 2009 Oct 27.
Published in final edited form as: Biol Psychiatry. 2006 Jan 10;60(1):22–31. doi: 10.1016/j.biopsych.2005.09.021

Table 2.

Diffusion Indices in the Fornix and Hippocampal Volume

Patients with Schizophrenia (n = 24)
 Control Subjects (n = 31)
Mean ± SD Mean ± SD t or F df p Value
Fornix
    FA .665 ± .071 .720 ± .065 2.963 53 .005a
    Dm × 10–3mm2/sec 1.240 ± .142 1.161 ± .134 –2.096 53 .041a
    Area, mm2 32.7 ± 7.6 38.7 ± 6.0 3.265 53 .002a
Intracranial Content, mL 1507 ± 114 1551 ± 105 1.464 53 .149a
Hippocampal Volume
    Left Absolute, mL 2.235 ± .316 2.531 ± .310
        Relative, % .149 ± .021 .164 ± .020
    Right Absolute 2.303 ± .263 2.603 ± .287
        Relative .153 ± .017 .168 ± .016
    Total Absolute 4.537 ± .557 5.134 ± .562 15.355 1,53 <.001b,c
        Relative .302 ± .037 .332 ± .034 9.557 1,53 .003b,d
a

t test.

b

Two-factor analysis of variance. Group as a between-subjects factor, hemisphere as a within-subject factor.

c

There was a significant main effect of hemisphere [F(1,53) = 7.513, p = .008] and no significant group-by-hemisphere interaction [F(1,53) = .006, p = .938].

d

There was a significant main effect of hemisphere [F(1,53) = 7.442, p = .009] and no significant group-by-hemisphere interaction [F(1,53) = .004, p = .950].