Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Proton and bicarbonate transport in the alpha-intercalated cell of the distal tubule. At the apical surface, hydrogen ions produced by the carbonic anhydrase-catalyzed hydration of CO2 are secreted via the ATP-driven hydrogen pump and hydrogen-potassium exchanger. At the basolateral membrane, bicarbonate is reabsorbed in exchange for chloride via the anion exchanger AE1. Chloride exits the cell through a separate channel. CA, carbonic anhydrase.
