Table 2.
31P MRS data at baseline and end of exercise.
| 31P MRS Variables | Normal Lean (N=15) | Sarcopenic (N=9) | P-Value |
|---|---|---|---|
| [PCr]mM Rest | 35.5 ± 1.8 | 36.4 ± 3.6 | 0.35 |
| [Pi] mM Rest | 3.4 ± 0.5 | 3.8 ± 0.4 | 0.02* |
| pH Rest | 6.99 ± 0.01 | 6.99 ± 0.02 | 0.98 |
| [ADP] μM Rest | 4.7 ± 0.6 | 5.3 ± 0.8 | 0.10 |
| [PCr]/[Pi] Rest | 10.6 ± 1.5 | 9.5 ± 1.3 | |
| ATP/[PCr] Rest | 0.0036 ± 0.0003 | 0.0035±0.0006 | 0.42 |
| ATP/[ADP] Rest | 0.0266 ± 0.0038 | 0.0234 ± 0.0028 | 0.03* |
| ΔGp Rest (kJ/mole) | −56.2 ± 0.6 | −55.7 ± 0.5 | 0.02* |
| [PCr] mM End of Exercise | 28.9 ± 3.8 | 28.7 ± 4.4 | 0.94 |
| [Pi] mM End of Exercise | 9.9 ± 6.7 | 9.8 ± 6.1 | 0.91 |
| pH End of Exercise | 7.03 ± 0.03 | 7.02 ± 0.06 | 0.62 |
| [ADP] μM End of Exercise | 15.9 ± 8.6 | 17.4 ± 9.3 | 0.72 |
| ΔGp End of Exercise (kJ/mole) | −52.12 ± 2.16 | −52.68 ± 2.70 | 0.06† |
| PCr t1/2 (seconds) | 43.8 ± 21.4 | 57.2 ± 36.9 | 0.19 |
Values are shown as means ± SD.
Significant difference between normal lean and sarcopenic group,
for trend in significance between normal lean and sarcopenic group (p<0.05).