Table 3.
Restricted distribution of HFOs
| Patient | Sample | Percentage channels with HFO detections | Percentage channels responsible for 50% of detections | Mean HFO to microdischarge sites distance | Expected distance for uniform distribution |
|---|---|---|---|---|---|
| 1 | Wake | 9 | 2.3 | N/A | N/A |
| Sleep | 15 | 3.5 | N/A | N/A | |
| 2 | Wake | 22 | 4.4 | 0.71 | 1.08 |
| Sleep | 24 | 4.4 | 0.83 | 1.08 | |
| 3 | Wake | 27 | 4.2 | 0.46 | 1.20 |
| Sleep | 30 | 6.3 | 0.71 | 1.20 | |
| 4 | Wake | 22 | 4.7 | 0.19 | 0.66 |
| Sleep | 28 | 5.8 | 0.25 | 0.66 |
HFOs are limited to small subregions of the MEA, as indicated both by the percentage of recording channels with any HFO detections and the percentage of channels responsible for half of HFO detections. HFO clusters also tended to be closer than expected to microdischarge sites, an effect that was found to be significant in each case (Wilcoxon signed rank test, P < 0.01).