Table 2.

Biodistribution of ^99mTc-HYNIC-Annexin-V in EL4 lymphoma and the number of apoptotic cells after single-dose irradiations

		Dose	(Gy)			p
	0	2	4	8	0 vs.2	2 vs.4	4 vs.8
%ID/g	0.160 ± 0.013	0.272 ± 0.021	0.312 ± 0.020	0.355 ± 0.025	<0.001	0.017	0.009
T/B	0.729 ± 0.037	1.252 ± 0.086	1.396 ± 0.021	1.661 ± 0.072	<0.001	0.005	<0.001
T/M	2.575 ± 0.154	4.522 ± 0.554	5.191 ± 0.511	7.138 ± 0.266	<0.001	0.039	<0.001
Apoptotic cells	1.405 ± 0.191	2.459 ± 0.370	4.364 ± 0.778	6.953 ± 0.673	0.002	0.004	0.002

Results expressed as mean ± SD. %ID/g = percentage injected dose per gram of tumor tissue; T: ^99mTc-HYNIC annexin-V uptake in tumor; B: ^99mTc-HYNIC-annexin V uptake in blood; M: ^99mTc-HYNIC annexin-V uptake in muscle. Apoptotic cells were counted as the number of TUNEL positive cells per mm² of each examined section.