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. 2009 Oct 14;7:111. doi: 10.1186/1477-7827-7-111

Table 9.

Mean gonadotropin doses required to achieve clinical pregnancy/live birth in the 865 ICSI cycles.

hMG HP-hMG r-hFSH Relative difference, %
hMG vs r-hFSH HP-hMG vs r-hFSH
Dose per clinical pregnancy, IU* 7563 7258 6536 15.7 11
 ≤35 years 7202 6695 5942 21.2 12.7
 >35 years 8456 8100 8020 5.4 1
Dose per live birth, IU* 10,170 8390 7000 45.3 19.8
 ≤35 years 9690 7739 6364 52.2 21.6
 >35 years 11,371 9364 8589 32.4 9

Mean gonadotropin doses required to achieve one clinical pregnancy or one live birth are presented, with relative differences for hMG and HP-hMG compared with r-hFSH.

*Calculated as the mean dose per cycle/clinical pregnancy rate or live birth rate.

hMG, human menopausal gonadotropin; HP-hMG, highly purified hMG; ICSI, intracytoplasmic sperm injection; r-hFSH, recombinant human follicle-stimulating hormone.