Table 6.

Estimated coefficients and P values from the repeated measures mixed effect model

	Patient reported outcomes
	FKSI-DRS	FKSI	FACT-G total	FACT-G PWB	FACT-G SWB	FACT-G EWB	FACT-G FWB	EQ-5D index	EQ-VAS
Intercept (β0)	6.267 (<0.0001)	6.202 (0.002)	4.469 (0.166)	4.010 (<0.0001)	4.115 (<0.0001)	3.738 (<0.0001)	1.984 (0.012)	0.133 (0.001)	18.101 (<0.0001)
Baseline score (β1)	0.687 (<0.0001)	0.743 (<0.0001)	0.844 (<0.0001)	0.659 (<0.0001)	0.745 (<0.0001)	0.741 (<0.0001)	0.754 (<0.0001)	0.691 (<0.0001)	0.649 (<0.0001)
Time (β2)	−0.002 (0.581)	−0.005 (0.272)	−0.010 (0.127)	−0.001 (0.723)	−0.002 (0.544)	0.0007 (0.712)	−0.006 (0.030)	0.0002 (0.271)	−0.002 (0.862)
Treatment (β3)	1.752 (<0.0001)	2.845 (<0.0001)	4.605 (<0.0001)	0.787 (0.158)	1.552 (<0.0001)	0.895 (0.019)	1.186 (0.019)	0.062 (0.022)	2.771 (0.100)
Time × treatment (β4)	0.007 (0.070)	0.010 (0.082)	0.019 (0.030)	0.006 (0.659)	0.0004 (0.910)	0.002 (0.513)	0.008 (0.022)	−0.0002 (0.514)	0.019 (0.105)

FKSI-DRS, Functional Assessment of Cancer Therapy–Kidney Symptom Index–Disease-Related Symptoms; FACT-G, Functional Assessment of Cancer Therapy-General; EQ-5D, EQ-5D self-report questionnaire; PWB, physical well-being; SWB, social well-being; EWB, emotional well-being; FWB, functional well-being.