Table 3.
Gene Expression Level (median of F and T) |
Event level (B/E ratio) |
||
Fold Change Set | Total Genes | Total Events | Subset of events with ≥3 Fold Change |
x ≥ 3 or ≤ -3 | 1844 | 13323 | 7883 |
-1.2 ≤ x ≤ 1.2 | 4434 | 32917 | 3012 |
Genes were classified into two groups: genes that were not differentially expressed between samples A and B (fold changes within the range of -1.2 ≤ x ≤ 1.2), and genes with a greater than 3-fold change (x ≤ -3 or x ≥ 3). In order to determine the differential splicing occurring for each gene, the ratio of the long form probe (B) and the short form probe (E) was calculated, and events were selected where the ratio was differentially expressed between samples A and B by greater than 3-fold.