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Concentration dependent DNA damage (black square) presented as median with first and third quantile, and cytotoxicity (black triangle) presented as mean with standard deviation, induced by cisplatin (A), or carboplatin (B). DNA damage was measured after a 24 h incubation, cytotoxicity after a 7 day incubation with the cytostatics. MMS alone induced a tail moment ranging from 80-90. The platinum compounds alone induced no tail moments.
