Table 2.
Neuropathological Data on Parkinson Disease, Dementia with Lewy Bodies and Alzheimer Disease Cases
| Case No. | Aβ stage | NF stage | Lewy stage | AD criteria | DLB criteria |
|---|---|---|---|---|---|
| PD1 | B | I | I> | ∼ | ∼ |
| PD2 | A | I | I> | ∼ | ∼ |
| DLB1 | C | IV | IV | ∼ | high (diffuse neocortical) |
| DLB2 | C | II | III | ∼ | high (diffuse neocortical) |
| DLB3 | 0 | II | IV | ∼ | high (diffuse neocortical) |
| DLB4 | C | II | III | ∼ | high (diffuse neocortical) |
| DLB5 | C | II | III | ∼ | high (diffuse neocortical) |
| DLB6 | C | II | III | ∼ | high (diffuse neocortical) |
| AD1 | C | V | ∼ | high | ∼ |
| AD2 | C | V | ∼ | high | ∼ |
| AD3 | C | IV | ∼ | high | ∼ |
| AD4 | C | V | ∼ | high | ∼ |
| AD5 | C | V | ∼ | high | ∼ |
| AD6 | C | V | ∼ | high | ∼ |
Amyloid β (Aβ) stages (A–C) and neurofibrillary (NF) stages (I–VI) were determined according to Braak staging (33). Lewy stages (I-IV) in DLB were assigned according to our previous protocol (34). Consensus criteria were used to diagnose PD (29), DLB (30) and AD (31). PD, Parkinson disease; DLB, dementia with Lewy bodies; AD, Alzheimer disease; ∼, not applicable.