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. Author manuscript; available in PMC: 2009 Oct 28.
Published in final edited form as: Int J Antimicrob Agents. 2005 Nov 7;26(6):486–490. doi: 10.1016/j.ijantimicag.2005.08.017

Table 1.

Mutations in the sequence encoding amino acid positions 90–96 of the gyrA gene, and the minimum inhibitory concentration (MIC) and phenotypic susceptibility to ciprofloxacin of Neisseria gonorrhoeae isolates (N = 40)

gyrA gene sequence No. of isolates Ciprofloxacin MIC (mg/L) Phenotypic ciprofloxacin susceptibility
Wild-type 9 0.002–0.047 Susceptible
S91P and D95A alterations 11 0.125–32 Decreased susceptibility to high resistance
S91P and D95G alterations 10 0.125–32 Decreased susceptibility to high resistance
S91P alteration 8 0.047–0.38 Susceptible
D95N alteration 2 0.032–0.064 Susceptible