Table 2.
Serum concentrations of lipopolysaccharide binding protein (LBP), soluble CD14, soluble tumour necrosis factor (TNF) receptor 55 kDa and interleukin (IL)-6 in healthy controls and patients with compensated and decompensated cirrhosis
Healthy controls (n = 20) | Cirrhotic patients without ascites (n = 20) | Differences: healthy controls versus compensated cirrhosis (P) | Cirrhotic patients with ascites (n = 20) | Differences: healthy controls versus decompensated cirrhosis (P) | Differences: compensated versus decompensated cirrhosis (P) | |
---|---|---|---|---|---|---|
LBP | 3·4 | 7·7 | < 0·001 | 28·2 | < 0·001 | < 0·001 |
(µg/ml) | (2·7–4·2) | (5·7–9·1) | (10·7–40·6) | |||
sCD14 | 2960 | 8455 | < 0·001 | 10790 | < 0·001 | n.s. |
(ng/ml) | (2354–3715) | (4581–10579) | (7590–12778) | |||
sTNF-RI | 144 | 232 | < 0·001 | 527 | < 0·001 | 0·008 |
(pg/ml) | (108–177) | (143–259) | (234–1406) | |||
IL-6 | 0 | 5 | < 0·001 | 26 | < 0·001 | < 0·001 |
(pg/ml) | (0–2) | (2–7) | (14–58) |
Variables are expressed as median (interquartile range). n.s., not significant.