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. Author manuscript; available in PMC: 2010 Sep 1.

Published in final edited form as: Circ Heart Fail. 2009 Jul 21;2(5):472–481. doi: 10.1161/CIRCHEARTFAILURE.109.853200

Average data at all 4 frequencies of developed force (A), RT₅₀ of force decline (B), RT₅₀ to RT₉₀ of force decline (C), diastolic tension relative to 1 Hz (D), diastolic and systolic calcium (E), RT₅₀ of intracellular calcium decline (F). Two-way repeated measures ANOVA revealed a significant interaction (indicated with ) between frequency and the two groups (indicating a difference in the relationship) with respect to developed force, RT₅₀ to RT₉₀, diastolic tension relative to 1 Hz, and systolic calcium. No significant interactions were found between frequency and the two groups with respect to RT₅₀ of force decline, diastolic calcium, or RT₅₀ of calcium decline. Analysis by each group separately by one-way ANOVA revealed a significant difference from 1 Hz in all 7 parameters measured (post-hoc t-test). * denotes significantly different compared to 1 Hz (PAB: n=11, SHAM: n=9).

Inline graphic — Average data at all 4 frequencies of developed force (A), RT₅₀ of force decline (B), RT₅₀ to RT₉₀ of force decline (C), diastolic tension relative to 1 Hz (D), diastolic and systolic calcium (E), RT₅₀ of intracellular calcium decline (F). Two-way repeated measures ANOVA revealed a significant interaction (indicated with ) between frequency and the two groups (indicating a difference in the relationship) with respect to developed force, RT₅₀ to RT₉₀, diastolic tension relative to 1 Hz, and systolic calcium. No significant interactions were found between frequency and the two groups with respect to RT₅₀ of force decline, diastolic calcium, or RT₅₀ of calcium decline. Analysis by each group separately by one-way ANOVA revealed a significant difference from 1 Hz in all 7 parameters measured (post-hoc t-test). * denotes significantly different compared to 1 Hz (PAB: n=11, SHAM: n=9).