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. 2009 Oct 26;206(11):2381–2395. doi: 10.1084/jem.20091007

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© 2009 Decrem et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 7. — Intravital microscopy images from mouse dorsal skinfold window chambers illustrating the effect of Ir-CPI on high light intensity–induced thrombosis. (A) Representative images of microvessels of 1-mg/kg Ir-CPI–treated (bottom) and untreated (top) mice. The vessels after injection of 10 mg/kg of rose bengal but before high light intensity stimulation (time, 0) are shown on the left. The same vessels 2 h after high light intensity excitation (time, 2 h) are shown on the right. Representative images of five experiments are shown. Bars, 100 µm. (B) Bar graph showing changes in blood flow velocity in untreated and Ir-CPI–treated mice (n = 5). Results are expressed as a percentage of initial flow measured in each vessel. Data represent the mean ± SEM of results obtained from five independent experiments. **, P < 0.01.