Table 4.
Genes differentially expressed in common among breast cancer cell lines resistant to MTX
| GenBank | Gene name | Description | Ratio MCF7 | Ratio MDA-MB-468 |
|---|---|---|---|---|
| NM_019093 | UGT1A1/3/4/5/6/7/8/9/10 | UDP glucuronosyltransferase 1, polypeptides A1/3/4/5/6/7/8/9/10 | 24.36 | 27.93 |
| NM_000463 | UGT1A1/4/6/8/9/10 | UDP glucuronosyltransferase 1, polypeptides A1/4/6/8/9/10 | 15.31 | 17.66 |
| NM_021027 | UGT1A1/4/6/8/9/10 | UDP glucuronosyltransferase 1, polypeptides A1/4/6/8/9/10 | 13.55 | 17.05 |
| NM_001072 | UGT1A1/3/4/5/6/7/8/9/10 | UDP glucuronosyltransferase 1, polypeptides A1/3/4/5/6/7/8/9/10 | 13.21 | 16.88 |
| AV691323 | UGT1A1/3/4/5/6/7/8/9/10 | UDP glucuronosyltransferase 1, polypeptides A1/3/4/5/6/7/8/9/10 | 13.05 | 16.82 |
Genes differentially expressed by at least twofold with a P-value < 0.05 including multiple testing correction were compared between MCF7 and MDA-MB-468 cells as described in Table 3.