Table 3.
Hazard ratios (95% confidence intervals) for death in survivors of an acute myocardial infarction (AMI) after stepwise addition of risk markers: Perth MONICA cohort 1984-93
1988-90 v 1984-7 | 1991-3 v 1984-7 | |
---|---|---|
Death at one year in 28 day survivors | ||
Unadjusted | 0.77 (0.53 to 1.11) | 0.60 (0.40 to 0.90) |
Adjusted for: | ||
Demographic factors (age and sex) | 0.76 (0.53 to 1.11) | 0.61 (0.40 to 0.91) |
Above plus coronary risk factors* | 0.76 (0.53 to 1.11) | 0.60 (0.40 to 0.91) |
Above plus disease severity† | 0.82 (0.56 to 1.19) | 0.64 (0.42 to 0.96) |
Above plus clinical complications during admission‡ | 0.83 (0.57 to 1.20) | 0.66 (0.44 to 1.01) |
Above plus medical treatment in hospital§ | 1.10 (0.72 to 1.69) | 1.00 (0.61 to 1.65) |
Death at 12 years in one year survivors | ||
Unadjusted | 0.88 (0.76 to 1.02) | 0.72 (0.62 to 0.84) |
Adjusted for: | ||
Demographic factors (age and sex) | 0.88 (0.76 to 1.01) | 0.72 (0.62 to 0.84) |
Above plus coronary risk factors* | 0.88 (0.76 to 1.01) | 0.71 (0.61 to 0.82) |
Above plus disease severity† | 0.93 (0.80 to 1.07) | 0.73 (0.63 to 0.85) |
Above plus clinical complications during admission‡ | 0.94 (0.82 to 1.09) | 0.74 (0.63 to 0.86) |
Above plus medical treatment in hospital§ | 1.19 (1.00 to 1.40) | 0.96 (0.79 to 1.16) |
Above plus CAR within 12 months | 1.38 (1.16 to 1.63) | 1.15 (0.94 to 1.40) |
CAR=coronary artery revascularisation.
*History of diabetes, history of hypertension, and current or recent smoker.
†Predicting risk of death in cardiac disease tool score (score 0-3 based on ischaemic ECG progression).14
‡Heart failure, cardiogenic shock, tachycardia>100 beats/minute, systolic blood pressure <100 mm Hg within 28 days of admission to hospital.
§Thrombolysis, antiplatelet, β blocker, angiotensin converting enzyme inhibitor, and lipid lowering drugs.