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. 2009 Oct;37(10):2112–2117. doi: 10.1124/dmd.109.027680

Fig. 3.

Fig. 3.

MicroRNA-27b and mmu-miR-298 may interact with VDR/NR1I1 3′UTR. A, individual MRE sites within VDR 3′UTR predicted by MicroInspector and/or TargetScan. The miR-27b MRE is well conserved in different species. B, HEK293 cells transfected with pS-miR-27b or pS-mmu-miR-298 plasmids showed lower VDR 3′UTR-luciferase reporter activities than the control. This effect appeared to be attenuated when cells were cotransfected with selective miRNA antagomir. ∗, P < 0.05 (n = 4 in each group; one-way ANOVA with Dunnett's posttest). See Materials and Methods for more details.