TABLE 2.
mRNAs Altered by Ahr Genotype
| Expression data |
||||||
| Entrez gene ID | Symbol | M (liver) | M (kidney) | p (liver) | p (kidney) | Name |
| 104923 | Adi1 | 3.74 | 5.18 | 3.52 × 10−4 | 1.70 × 10−3 | Acireductone dioxygenase 1 |
| 13370 | Dio1 | 1.63 | 2.06 | 7.28 × 10−4 | 1.92 × 10−5 | Deiodinase, iodothyronine, type I |
| 105892 | 9030619P08Rik | 0.42 | 1.10 | 1.39 × 10−2 | 3.17 × 10−3 | RIKEN cDNA 9030619P08 gene |
| 71670 | Acy3 | 0.79 | 0.62 | 2.61 × 10−3 | 2.28 × 10−3 | Aspartoacylase (aminoacylase) 3 |
| 108114 | Slc22a7 | 3.15 | 0.53 | 7.93 × 10−6 | 9.38 × 10−3 | Solute carrier family 22 (organic anion transporter), member 7 |
| 70337 | Iyd | −0.33 | 0.44 | 1.80 × 10−2 | 2.82 × 10−3 | Iodotyrosine deiodinase |
| 13476 | Reep5 | 0.57 | 0.38 | 8.55 × 10−3 | 8.45 × 10−3 | Receptor accessory protein 5 |
| 68347 | 0610011F06Rik | 0.49 | 0.37 | 3.76 × 10−3 | 3.17 × 10−3 | RIKEN cDNA 0610011F06 gene |
| 19703 | Renbp | −0.40 | −0.43 | 3.31 × 10−2 | 3.52 × 10−3 | Renin binding protein |
| 50490 | Nox4 | 0.90 | −0.44 | 2.22 × 10−2 | 8.40 × 10−3 | NADPH oxidase 4 |
| 15211 | Hexa | −0.60 | −0.46 | 2.84 × 10−4 | 1.70 × 10−3 | Hexosaminidase A |
| 109900 | Asl | −0.76 | −0.56 | 6.85 × 10−3 | 3.46 × 10−4 | Argininosuccinate lyase |
| 67442 | Retsat | 0.62 | −0.60 | 4.00 × 10−2 | 4.81 × 10−3 | Retinol saturase (all trans retinol 13,14 reductase) |
| 14873 | Gsto1 | −0.75 | −0.66 | 3.52 × 10−4 | 1.70 × 10−3 | Glutathione S-transferase omega 1 |
| 17748 | Mt1 | −6.74 | −0.74 | 3.83 × 10−6 | 1.70 × 10−3 | Metallothionein 1 |
Note. A listing of a subset of genes whose mRNA abundances were altered by Ahr genotype in both kidney and liver. The Entrez Gene ID is a stable gene identifier. The M values give the fold-changes of differential abundance in log2 space. For example, the M (Liver) of 3.74 for Adi1 indicates a 13.4-fold increase in abundance in the liver of animals with a wild-type Ahr relative to Ahr−/− animals. p Values have been subjected to a false-discovery rate adjustment for multiple testing.