Figure 4.

Normal performance of GluN1^Rneo/+ mice in motor-coordination and novel object recognition tasks. (A) Rotarod test. Latencies of GluN1^Rneo/+ (n = 12) and wild-type GluN1^+/+ littermates (n = 8) over three training days. No difference in performance was observed between the genotypes over the 3 d of training. (B) Novel object recognition. The two genotypes showed equivalent performance when tested shortly (1-min interval) after training. Neither genotype retained a preference for the novel object when tested 1 h after training. GluN1^Rneo/+ (n = 8) and wild-type GluN1^+/+ littermates (n = 6).