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. 2009 Oct 5;119(11):3450–3461. doi: 10.1172/JCI38432

Figure 2. Priming with i.p. LPS restores lung injury after MHC I mAb challenge.

Figure 2

(A and B) Extravascular lung water and EVPEs in barrier mice administered i.p. LPS (0.1 mg/kg) with and without increasing doses of MHC I mAb. **P < 0.05 vs. 0 mg/kg H2Kd mAb; †P < 0.05 vs. 0.5, 1.0, 2.25, and 4.5 mg/kg H2Kd mAb. (C) Survival curves from mice in A and B. P = 0.02 (Fisher’s exact) for trend of increasing mortality, with increasing dose of MHC I mAb.