Figure 3. LPS i.p. plus MHC I mAb produces severe ALI with hemoconcentration.
(A–C) Representative H&E-stained lung sections from (A) a control mouse, (B) a mouse given i.p. LPS (24 hours at 0.1 mg/kg), and (C) a mouse given i.p. LPS (0.1 mg/kg) and MHC I mAb (1.0 mg/kg) at 2 hours after injection. Note intra-alveolar edema fluid in C. Original magnification, ×200. (D) Hematocrit response in barrier mice administered i.p. LPS (0.1 mg/kg) with or without MHC I mAb. **P < 0.05 vs. all other groups, †P < 0.05 vs. all other groups, ††P < 0.05 vs. all other groups.