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Flow cytometric analysis of lymphoid cells in peripheral blood after administration of T10B9.1A-31, OKT3 or TCR-1 (anti-T cell receptor αβ monoclonal antibody [mAB]). There is early T-lymphocyte depletion with re-expression of the CD4 and CD8 epitopes. There is persistent modulation of the CD3/TCR αβ region in these phenotypically altered T cells for 10 days while the mABs are being administered with repopulation over 15–40 days.
