Table 1.
Descriptive analysis for colorectal cancer cases overall and based on ODC1 genotype
| All CRC Cases n = 400 |
ODC1 GG n = 208 |
ODC1 GA/AA n = 192 |
P-value | ||
|---|---|---|---|---|---|
| Median Age (with age range) | 56.6 (29-89) | 56.8 (29-89) | 56.4 (29-82) | 0.24 | |
| Gender | Male | 230 (58%) | 117 (56%) | 113 (59%) | 0.60 |
| Female | 170 (41%) | 91 (44%) | 79 (41%) | ||
| Ethnicity | Non-Hispanic Caucasian | 351 (88%) | 188 (90%) | 163 (85%) | 0.14 |
| African American | 4 (1%) | 2 (1%) | 2 (1%) | ||
| Caucasian-Hispanic | 20 (5%) | 11 (5%) | 9 (5%) | ||
| Asian | 23 (6%) | 7 (3%) | 16 (8%) | ||
| Other | 2 (<1%) | 0 (0%) | 2(1%) | ||
| Family History of CRC | Yes | 106 (26%) | 56 (27%) | 50 (26%) | 0.84 |
| No | 294 (74%) | 152 (73%) | 142 (74%) | ||
| Stage at Diagnosis | I | 146 (37%) | 72 (35%) | 74 (39%) | 0.49 |
| II | 128 (32%) | 72 (35%) | 56 (29%) | ||
| III | 126 (31%) | 64 (31%) | 62 (32%) | ||
| Colon/Rectum Site | Proximal and transverse | 120 (30%) | 65 (31%) | 55 (29%) | 0.90 |
| Descending | 22 (6%) | 12 (6%) | 10 (5%) | ||
| Sigmoid | 110 (28%) | 55(26%) | 55 (29%) | ||
| Rectosigmoid | 57 (14%) | 32 (15%) | 25 (13%) | ||
| Mid-Low Rectum | 86 (22%) | 41 (20%) | 45 (23%) | ||
| Colorectum, unspecified | 5 (1%) | 3 (1%) | 2 (1%) | ||
| Histologic Subtype | Adenocarcinoma Mucinous | 364 (91%) | 183 (88%) | 181 (94%) | 0.16 |
| adenocarcinoma | 26 (7%) | 18 (9%) | 8 (4%) | ||
| Carcinoma | 9 (2%) | 6 (3%) | 3 (2%) | ||
| NOS | 1 (<1%) | 1 (<1%) | 0 (0%) | ||
| Tumor Grade | I | 62 (17%) | 27 (14%) | 35 (20%) | 0.36 |
| II | 261 (71%) | 140 (73%) | 121 (68%) | ||
| III | 46 (13%) | 24 (13%) | 22 (12%) | ||
| No. missing | 31 | 17 | 14 | ||
| Surgical Treatment | Yes | 395 (99%) | 204 (98%) | 191 (99%) | 0.21 |
| No | 5 (1%) | 4 (2%) | 1 (1%) | ||
| Radiation Therapy | Yes | 63 (16%) | 29 (14%) | 34 (18%) | 0.30 |
| No | 337 (84%) | 179 (86%) | 158 (82%) | ||
| Chemotherapy | Yes | 170 (45%) | 84 (44%) | 86 (46%) | 0.56 |
| No | 208 (55%) | 109 (56%) | 99 (54%) | ||
| No. missing | 22 | 15 | 7 | ||