Biodistribution of MV-NIS genome in IfnarKO × CD46 Ge mice after intravenous administration of 107 TCID50 MV-NIS day 0 with and without 125 mg/kg cyclophosphamide (CP) pretreatment day −1. (a) Day 2, (b) day 5, (c) day 22, (d) day 91. Data normalized per microgram of total RNA. Closed diamonds, without CP; open diamonds, with CP; black, brain; red, lung; blue, liver; orange, kidney; green, spleen; purple, blood; and brown, gonads. Limit of detection (LOD) of QRT-PCR assay is 100 copies of MV nucleoprotein RNA per microgram of total RNA.