Table 2.
Study day |
|||||
---|---|---|---|---|---|
MV-NIS | CP | 8 | 15 | 29 | 91 |
+ | − | <30 | 2,430 | 2,430 | |
+ | − | <30 | 810 | 270 | |
+ | − | <30 | 7,290 | 2,430 | 810 |
+ | + | <30 | 2,430 | 2,430 | |
+ | + | <30 | 2,430 | 1,620 | |
+ | + | 30 | 2,430 | 1,620 | 810 |
MV-NIS, measles virus encoding the human thyroidal sodium iodide symporter; TCID50, tissue culture infectious dose 50. Two monkeys from each group were euthanized for histology at day 29. Pretest levels were confirmed as negative (data not shown).