Normal (top) and Type 2 Diabetic (bottom) windows. Each window is divided into three sections that allow the user to set basal values of glucose concentration, insulin concentration, and glucose production (glucose clearance is calculated and displayed in the proper square); to enter values of body weight and main metabolic indices, such as peripheral and hepatic insulin sensitivity, static, and dynamic beta-cell responsivity to glucose (as percentage of normal values); and to define the time of the three meals and the amount of glucose ingested. The window also shows buttons to start simulation, save the simulated profiles, or run a new subject.