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Model-predicted GCR response to glucose decline (top) or lack of decline (bottom) and a combined INS and SS intrapancreatic infusion in which SS but not INS has been switched off during hypoglycemia. Glucagon is shown by the lower black line; endogenous SS is shown by the upper black line; INS infusion is represented by a densely dotted line; exogenous SS infusion is shown by a dashed line; and BG is shown by a sparsely dotted line.
