Table 5.
Comparison of Glycemic Control Performance between Retrospective Control, Typical Sliding Scale Control, and Targeted Model-Based Control with Increasing Blood Glucose Measurement Interval
| Control scheme | Measurement frequency (h) | Total measurements | Median BG (mg/dl) | BG IQR (mg/dl) | % of measurements within range | Average insulin (U/kg/h) × 10−2 | ||
|---|---|---|---|---|---|---|---|---|
| 72–126 mg/dl | 72–144 mg/dl | <47 mg/dl | ||||||
| Model-based controller | 1 | 3555 | 110 | 101–119 | 81.7% | 90.1% | 0.23% | 5.4 |
| 2 | 1771 | 108 | 97–122 | 76.1% | 86.4% | 0.45% | 5.6 | |
| 3 | 1175 | 108 | 95–126 | 69.3% | 81.3% | 0.60% | 5.7 | |
| 4 | 879 | 110 | 94–130 | 64.6% | 76.3% | 0.91% | 5.5 | |
| Retrospective | 1091 | 144 | 113–178 | 30.9% | 45.6% | 0.73% | 3.4 | |
| Sliding scale | 1 | 3555 | 155 | 122–187 | 26.0% | 40.1% | 0.20% | 2.9 |
| 2 | 1771 | 155 | 124–189 | 24.8% | 39.5% | 0.34% | 2.9 | |
| 3 | 1175 | 153 | 122–191 | 24.9% | 40.9% | 0.34% | 3.0 | |
| 4 | 879 | 153 | 124–194 | 25.0% | 41.4% | 0.57% | 3.0 | |