Table 2.

Putative Determinants of the Value of Principal Parameters of the Algorithm Discoverable in Nature and Not User Defined^a

		Putative determinants of parameter value
Parameter	Units of measure	C6R and HGOmax	Endogenous insulin production	Peripheral and hepatic insulin resistance	Body weight
ROAmax	mg/dl per hour	+	0	0	0
G-per-DIEM	mg/dl	+	+	0	0
MR/kg	units/h per kg	+	+	+	0
MR	units/h	+	+	+	+

^aROA_max, nonhypoglycemic maximum rate of ascent of blood glucose during negligible insulin infusion; G-per-DIEM, glucose flux per daily dose of insulin, exogenously mediated; MR, maintenance rate of insulin infusion; C6R, ambient rate of infusion of carbohydrate per hour; HGO_max, maximum hepatic glucose output during negligible insulin infusion under nonhypoglycemic ambient conditions.