Table 1.
Integral Method Performance Compared to Metrics Obtained by Mari18 Using a Deconvolution Approach on Same Dataa
| ISRb | ISR1 | ISR2 | |
|---|---|---|---|
| Mean (SEMb) in pmol · min-1 · m-2 | |||
| NGT | |||
| Deconvolution | 71 (7) | 900 (233) | 127 (37) |
| Integral method | 71 (10) | 851 (216) | 132 (25) |
| Correlation (P < 0.001) | 0.93 | 1.00 | 0.95 |
| T2DM | |||
| Deconvolution | 141 (29) | 218 (120) | 121 (31) |
| Integral method | 136 (30) | 277 (136) | 130 (34) |
| Correlation (P < 0.001) | 0.98 | 1.00 | 0.99 |
a
ISRb is basal secretion rate, ISR1 is mean secretion rate over basal in the 6-minute postglucose injection, and ISR2 is mean secretion rate over basal from 7 minutes until glucose reaches basal levels. Values from this study are converted to match units used by Mari.18
b
Standard error of the mean.