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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Trends Endocrinol Metab. 2009 Sep 7;20(8):402–408. doi: 10.1016/j.tem.2009.05.002

Figure 3.

Figure 3

Homo- and hetero-oligomerization of G protein-coupled receptors expressed in GnRH neurons. The expression of kisspeptin and GPR54 mRNAs in identified hypothalamic GnRH neurons and the constitutive and agonist-induced hetero-oligomerization of GnRH-R and GPR54 indicate that both receptors are involved in the regulating GnRH neuronal function. Green and red lines indicate stimulatory and inhibitory actions, respectively.