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. 2009 Jun 24;81(5):842–849. doi: 10.1095/biolreprod.109.077446

FIG. 1.

FIG. 1.

Ctnnb1tm1Mmt/+;Tg(AMH-cre)1Flor male mice develop testicular tumors. A) Normal testes of control males at 8 mo of age (arrows; left) and testicular tumor developed in the Ctnnb1tm1Mmt/+;Tg(AMH-cre)1Flor male mice at 8 mo of age (arrows; right). B) Incidence of the testicular tumor development in Ctnnb1tm1Mmt/+;Tg(AMH-cre)1Flor male mice. No tumors were found in mutant mice at 4 mo of age, but more than 70% of the mutant males (n = 10 of 13) developed tumors at 8 mo of age. The incidence increased to more than 90% at 1 yr of age (n = 12 of 13).