Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Jun 24;81(5):842–849. doi: 10.1095/biolreprod.109.077446

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2009 by the Society for the Study of Reproduction, Inc.

PMC Copyright notice

FIG. 2. — Tumor progression in Ctnnb1^tm1Mmt/+;Tg(AMH-cre)1Flor male mice. Aa–Af) Normal histology in testes of 4-mo-old control males (low magnification, Aa; high magnification, Ad), and progressive development of testicular tumors in Ctnnb1^tm1Mmt/+;Tg(AMH-cre)1Flor males of different ages (low magnification, Ab and Ac; high magnification, Ae and Af), shown by hematoxylin and eosin staining. Ag–Ai) Immunostaining with Leydig cell marker 3β-HSD identified Leydig cells in testes of Ctnnb1^tm1Mmt/+;Tg(AMH-cre)1Flor and control mice at different ages. B) β-Catenin (red) and WT1 (green) immunostaining on control testes and tumors. Tumor cells were positive for β-catenin and WT1 staining, indicating their Sertoli cell origin (Bb and Bd, respectively). Bar = 250 μm (Aa–Ac) and 100 μm (Ad–Bd).