Skip to main content
. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Virus Res. 2009 Apr 18;144(1-2):117–122. doi: 10.1016/j.virusres.2009.04.006

Figure 2.

Figure 2

Papilloma outgrowth by four pairs of two dysfunctional CRPV mutant genomes. Significantly smaller papillomas were found at sites challenged with four pairs of genome mixtures: 1) CRPV with an early stop codon in E6 (PJF75, 5μg) together with CRPV with 3bp deletion in E2 transactivation domain plus G907A in E6 (PJF192, 5μg) ; 2) PJF75 (5μg) with 3bp deletion in E2 transactivation domain plus G974A (PJF170, 5μg); 3) CRPV with E7ATGko (PJF185, 5μg) with PJF170 (5μg) ; 4) PJF185 (5μg) with PJF192 (5μg) when compared to those challenged with wild type CRPV DNA (P<0.05, unpaired student T test). No significant difference in papilloma size was found between these four pairs of mixtures (P>0.05, unpaired student T test).