Table 5. DNA-binding assay by DBD-Threader on C2H2/C2HC zinc finger domains involved in protein-protein interactions.
| Protein | ZF Domain | DBDT | Total (+/−) |
| FOG1 | ZF1, 4§ | −,+ | 1/1 |
| IKZF4/Eos | ZF5,6 | −,− | 0/2 |
| GLI1 | ZF1 | − | 0/1 |
| ZNF423/OAZ | ZF14–19 | −,−,−,−,−,− | 0/6 |
| ZBT16/PLZF | ZF1,2,8,9 | −,−,+,+ | 2/2 |
| ZBT32/FAZF | ZF1–3 | +,−,− | 1/2 |
| Total | 18 | 4/14 |
Proteins were taken from tables 2 and 3 of reference [60]. We excluded two sequences from mouse, one (the ortholog of ZNF423/OAZ) from rat, and a long sequence (MBP-1, 2,700 AAs) not assessed by DBD-Threader. Protein EEA1 was not included because it has only one zinc finger domain and it was not detected by threading. We also discarded zinc finger domains known DNA-binding, e.g., domains from Sp1, YY1, Zac1, and BCL6. The vast majority of these DNA-binding domains, if not all, are positives. Plus and minus signs denote the positive and negative DNA-binding assessment on individual domains by DBD-Threader.