Table 2. Conformational characteristics of hu3S193-bound Ley tetrasaccharides.
Fab-Ley complex | Fucα1-2Gala | Galβ1-4GlcNAc | Fucα1-3GlcNAc | |||
φ | ψ | φ | ψ | φ | ψ | |
1S3K | −78.1 | 140.4 | −77.6 | 139.2 | −77.8 | −103.4 |
Fab1 | −74.8 | 132.9 | −78.1 | 134.2 | −77.5 | −102.5 |
The glycosidic dihedral angles φ and ψ (°) are defined as O5−C1−O1−Cx and C1−O1−Cx−Cx−1, respectively. Values of glycosidic dihedrals for other free and bound Lewis system oligosaccharides were previously reported [26].