Table 2.
FSI total score and domain scores
| FSI domain | Baseline score [mean (SD)] | Endpoint score | ||||
|---|---|---|---|---|---|---|
| LS mean change from baseline (SE) | Difference in LS means | |||||
| Atomoxetine (N = 49) | Placebo (N = 50) | Atomoxetine (N = 49) | Placebo (N = 50) | Estimate (95% CI) | P value | |
| Total score | 9.8 (4.7) | 8.8 (4.6) | −2.2 (0.6) | −0.5 (0.6) | −1.8 (–3.5; 0.0) | 0.046 |
| Emotional | 3.4 (1.7) | 3.3 (1.7) | −0.8 (0.2) | −0.3 (0.2) | −0.5 (−1.1; 0.1) | 0.102 |
| Restriction | 6.5 (3.2) | 5.5 (3.3) | −1.4 (0.5) | −0.1 (0.5) | −1.2 (−2.5; 0.0) | 0.056 |
Baseline and change from baseline to endpoint
FSI family strain index, N maximum number of patients, SD standard deviation, LS least square, SE standard error, CI confidence interval