Table 3.
ASCR score | Baseline score [mean (SD)] | Endpoint score | ||||
---|---|---|---|---|---|---|
LS mean change from baseline (SE) | Difference in LS means | |||||
Atomoxetine (N = 49) | Placebo (N = 50) | Atomoxetine (N = 49) | Placebo (N = 50) | Estimate (95% CI) | P value | |
Section (I) | ||||||
Acceptance | 2.91 (0.36) | 2.82 (0.50) | 0.01 (0.05) | 0.02 (0.05) | −0.01 (−0.15; 0.13) | 0.888 |
Coping | 2.76 (0.28) | 2.83 (0.31) | 0.07 (0.04) | −0.04 (0.04) | 0.10 (−0.01; 0.22) | 0.069 |
Experiencing problems | 3.20 (0.43) | 3.11 (0.37) | 0.01 (0.05) | 0.03 (0.05) | −0.01 (−0.15; 0.13) | 0.871 |
Need for a change | 3.35 (0.59) | 3.37 (0.45) | 0.12 (0.06) | 0.07 (0.06) | −0.05 (−0.11; 0.21) | 0.549 |
Child as a burden | 3.29 (0.39) | 3.15 (0.44) | −0.18 (0.06) | 0.05 (0.06) | −0.24 (−0.41; −0.06) | 0.007 |
Managing on ones own | 2.92 (0.42) | 2.88 (0.38) | 0.09 (0.05) | 0.08 (0.05) | 0.02 (−0.12; 0.16) | 0.797 |
Pleasure | 1.76 (0.58) | 1.69 (0.57) | −0.19 (0.07) | −0.13 (0.07) | −0.06 (−0.25; 0.12) | 0.496 |
Relation | 3.26 (0.55) | 3.33 (0.63) | 0.12 (0.07) | 0.13 (0.07) | −0.01 (−0.21; 0.18) | 0.889 |
Section B | 4.53 (1.43) | 4.52 (1.38) | −0.57 (0.15) | −0.36 (0.15) | −0.21 (−0.63; 0.21) | 0.325 |
Baseline and change from baseline to endpoint
ASCR appraisal of stress in child-rearing, N maximum number of patients, SD standard deviation, LS least square, SE standard error, CI confidence interval