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Overview of hypocretin and MCH cell counts. Patients with traumatic brain injury (TBI) have fewer hypocretin neurons. On average, TBI patients have a total of 23,655 hypocretin neurons, whereas controls have 32,318 neurons (p = 0.001). The numbers of hypocretin neurons on the left and right sides of the hypothalamus differ more in TBI patients, probably reflecting asymmetry of the trauma. TBI patients also have fewer MCH neurons than controls (39,540 in total vs. 57,176, p = 0.06).
