Graph of the density (per 10μm3) of TH-labeled (TH+) terminals forming synapses are shown for controls (NC), treatment responsive (TR) and treatment resistant (TNR) subjects with schizophrenia. Total refers to all TH-labeled synapses regardless of subtype. SS, symmetric axospinous; SD, symmetric axodendritic. Error bars = standard deviation. ANOVA results: TH-labeled Total, p<0.057; TH-labeled SS, p<0.888; TH-labeled SD, p<0.017. Posthoc LSD t-tests show significant (*) results comparing TR to NCs or to TNR. There were no differences between the NCs and the TR-. *, p<0.05.