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. Author manuscript; available in PMC: 2009 Oct 29.
Published in final edited form as: J Immunol. 2009 Jun 15;182(12):7729–7737. doi: 10.4049/jimmunol.0803281

FIGURE 5.

FIGURE 5

BCR Induction of BAFF-R and its substrate p100 requires c-Rel. A–C, Kinetic analysis of BAFF-R and p100 in WT and crel−/− B cells. Naive splenic B cells from WT and c-Rel deficient mice were stimulated with anti-IgM F(ab′)2 10 μg/ml for the indicated times. RNA levels of BAFF-R, p100 were determined by qRT-PCR analysis. Relative fold induction was normalized to GAPDH and calibrated to the nonstimulated sample for each population. Mean data and SD from three experiments. C, Western blot analysis of total cellular extracts from WT and c-Rel deficient splenic B cells stimulated as in A for the indicated times. Blot was probed with anti-p100 and β-tubulin Abs. Data are representative of three experiments.