Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Proposed hypotheses for the myelin deficits observed in long‐term survivors of periventricular leukomalacia (PVL) in association with preserved Olig2 cell density. A. arrest in the maturation of the oligodendrocyte lineage (OL) progenitor (NG2) to a more mature myelin basic protein‐ (MBP) positive phenotype; B. inability of the mature OL to produce sufficient myelin [note hang‐up of MBP (brown) in the perikaryon]; C. primary axonal injury leading to axonal‐OL communication breakdown.
