. Author manuscript; available in PMC: 2009 Oct 29.

Published in final edited form as: Am J Kidney Dis. 2007 Mar;49(3):365–372. doi: 10.1053/j.ajkd.2006.12.016

Table 5.

Association of Preclinical Kidney Disease and CKD^† With Poor Exercise Capacity (METs < 5) and Poor HRR (<16 beats/min)

	Normal Kidney Function	Pre-CKD	P	CKD	P
Poor exercise capacity
Unadjusted OR (95% CI)	—	3.7 (2.4-5.5)	<0.0001	5.1 (3.2-7.9)	<0.0001
Adjusted OR (95% CI)^*	—	2.2 (1.3-3.9)	0.005	2.8 (1.5-5.3)	0.002
Poor HRR
Unadjusted OR (95% CI)	—	2.5 (1.7-3.6)	<0.0001	3.5 (2.3-5.3)	<0.0001
Adjusted OR (95% CI)^*	—	1.7 (1.0-2.7)	0.04	2.2 (1.3-3.9)	0.004

Adjusted for all variables in Table 1 (except kidney function variables).

^†

Normal kidney function defined as eGFR greater than 60 mL/min (>1.00 mL/s) and cystatin C level less than 1.0 mg/L. Pre-CKD defined as eGFR greater than 60 mL/min (>1.00 mL/s) and cystatin C level of 1.0 mg/L or greater. CKD defined as eGFR less than 60 mL/min (<1.00 mL/s).